Title : Cyp26 genes a1, b1 and c1 are down-regulated in Tbx1 null mice and inhibition of Cyp26 enzyme function produces a phenocopy of DiGeorge Syndrome in the chick.

Pub. Date : 2006 Dec 1

PMID : 17047027






1 Functional Relationships(s)
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1 Expression of the RA synthesizing enzyme Raldh2 was also up-regulated and altered Hoxb1 expression indicated that RA levels are raised in R115866-treated embryos as reported for Tbx1 null mice. Tretinoin aldehyde dehydrogenase family 1, subfamily A2 Mus musculus