Title : Investigation of the dimer interface and substrate specificity of prolyl dipeptidase DPP8.

Pub. Date : 2006 Dec 15

PMID : 17040910






1 Functional Relationships(s)
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1 Four conserved residues in the C-terminal loop of DPP8 (Phe(822), Val(833), Tyr(844), and His(859)), corresponding to those located at the dimer interface of DPP-IV, were individually mutated to Ala. Tyrosine dipeptidyl peptidase 4 Homo sapiens