Pub. Date : 1991 Jan
PMID : 1702097
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Northern blotting revealed significant increases in TGF-beta mRNA in bleomycin-stimulated endothelial cells. | Bleomycin | transforming growth factor, beta 1 | Rattus norvegicus |
| 2 | Thus in vitro stimulation of endothelial cells by bleomycin upregulates TGF-beta production, presumably by increased transcription. | Bleomycin | transforming growth factor, beta 1 | Rattus norvegicus |
| 3 | In view of the chemotactic and matrix synthesis stimulatory properties of this cytokine, such an increase in TGF-beta production may play an important role in bleomycin-induced pulmonary fibrosis. | Bleomycin | transforming growth factor, beta 1 | Rattus norvegicus |