Pub. Date : 2006
PMID : 17016062
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | New evidence of H1-receptor independent COX-2 inhibition by fexofenadine HCl in vitro. | fexofenadine | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
2 | The inhibition of COX-2 activity by FEX was similar to that seen with the selective COX-2 inhibitor, DuP-679. | fexofenadine | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
3 | CONCLUSION: FEX showed selective arachidonic acid-mediated COX-2 inhibitory enzyme activity, which differed markedly from the COX inhibitory enzyme activity of LOR. | fexofenadine | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
4 | This selective COX-2 inhibitor activity by FEX may contribute to its anti-inflammatory properties in relieving nasal congestion in allergic rhinitis. | fexofenadine | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |