Title : Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase.

Pub. Date : 2006 Oct

PMID : 17003332






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase. Fatty Acids interleukin 6 Homo sapiens
2 IL-6 treatment increased fatty acid oxidation, basal and insulin-stimulated glucose uptake, and translocation of GLUT4 to the plasma membrane. Fatty Acids interleukin 6 Homo sapiens
3 Our results demonstrate that acute IL-6 treatment enhances insulin-stimulated glucose disposal in humans in vivo, while the effects of IL-6 on glucose and fatty acid metabolism in vitro appear to be mediated by AMPK. Fatty Acids interleukin 6 Homo sapiens