Pub. Date : 2007 Jan
PMID : 17003231
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Cyclooxygenase, p38 mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinase MAPK, Rho kinase, and Src mediate hydrogen peroxide-induced contraction of rat thoracic aorta and vena cava. | Hydrogen Peroxide | Eph receptor B1 | Rattus norvegicus |
2 | Our data suggest that, in rat thoracic aorta and vena cava, a COX-derived metabolite is one important mediator of H2O2 contraction, possibly via rho kinase activation, and that H2O2-induced contraction via p38 and Erk MAPK probably occurs independently of TXA2 receptor activation. | Hydrogen Peroxide | Eph receptor B1 | Rattus norvegicus |