Pub. Date : 1990 Nov
PMID : 1700277
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In Y1 cells transfected with 2,327 base pairs of the human P450scc promoter fused to the bacterial gene for chloramphenicol acetyltransferase (CAT), forskolin increased CAT activity 900% while combined TPA plus A23187 reduced CAT activity to 15% of the control level. | Colforsin | cytochrome P450 family 11 subfamily A member 1 | Homo sapiens |
2 | Forskolin induced the P450scc promoter as rapidly as a promoter containing two cAMP-responsive elements fused to a simian virus 40 promoter, a system known to respond directly to cAMP. | Colforsin | cytochrome P450 family 11 subfamily A member 1 | Homo sapiens |