Title : Resveratrol modulates phorbol ester-induced pro-inflammatory signal transduction pathways in mouse skin in vivo: NF-kappaB and AP-1 as prime targets.

Pub. Date : 2006 Nov 30

PMID : 16999939






3 Functional Relationships(s)
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Protein Name
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1 Besides NF-kappaB, the p38 MAP kinase-mediated activation of activator protein-1 (AP-1) has also been attributed to TPA-induced COX-2 expression in mouse skin. Tetradecanoylphorbol Acetate jun proto-oncogene Mus musculus
2 Besides NF-kappaB, the p38 MAP kinase-mediated activation of activator protein-1 (AP-1) has also been attributed to TPA-induced COX-2 expression in mouse skin. Tetradecanoylphorbol Acetate jun proto-oncogene Mus musculus
3 Among the MAP kinases, extracellular signal-regulated protein kinase (ERK) and p38 MAP kinase have been shown to regulate TPA-induced NF-kappaB activation, while p38 MAP kinase and c-Jun-N-terminal kinase are preferentially involved in TPA-induced activation of AP-1 in mouse skin in vivo. Tetradecanoylphorbol Acetate jun proto-oncogene Mus musculus