Title : Activation of insulin-like growth factor type-1 receptor is required for H2O2-induced PKB phosphorylation in vascular smooth muscle cells.

Pub. Date : 2006 Jul

PMID : 16998541






2 Functional Relationships(s)
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1 In this study, we used pharmacological inhibitors to investigate the role of receptor and Src-family-PTKs in H2O2-induced PKB phosphorylation. Hydrogen Peroxide SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens
2 Moreover, H2O2-induced PKB phosphorylation was associated with increased tyrosine phosphorylation of c-Src and Pyk2 in an AG1024- and PP2-inhibitable manner. Hydrogen Peroxide SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens