Title : blm3-1 is an allele of UBP3, a ubiquitin protease that appears to act during transcription of damaged DNA.

Pub. Date : 2006 Oct 27

PMID : 16997324






3 Functional Relationships(s)
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Protein Name
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1 Both the blm3-1 and blm10-Delta mutations were reported to cause sensitivity to bleomycin and other forms of DNA damage, suggesting a role for Blm10/PA200-proteasome complexes in DNA repair. Bleomycin Blm10p Saccharomyces cerevisiae S288C
2 Both the blm3-1 and blm10-Delta mutations were reported to cause sensitivity to bleomycin and other forms of DNA damage, suggesting a role for Blm10/PA200-proteasome complexes in DNA repair. Bleomycin Blm10p Saccharomyces cerevisiae S288C
3 These results remove key components of the previously reported connection between Blm10/PA200-proteasome complexes and DNA repair, and they suggest a novel way to interpret sensitivity to bleomycin as resulting from defects in transcription elongation. Bleomycin Blm10p Saccharomyces cerevisiae S288C