Title : Involvement of some large immunophilins and their ligands in the protection and regeneration of neurons: a hypothetical mode of action.

Pub. Date : 2006 Oct

PMID : 16996313






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The drugs form complexes with diverse FKBPs but apparently the FKBP52/FK506 complex was shown to be involved in the protection and regeneration of neurons. Tacrolimus FKBP prolyl isomerase 4 Homo sapiens
2 It is proposed that binding of the FKBP52/FK506 complex to the membranes via the TPR motifs and its interaction with some membrane proteins could be in part responsible for some neuro-regeneration and neuro-protection of the brain during some ischaemia-induced stresses. Tacrolimus FKBP prolyl isomerase 4 Homo sapiens