Title : An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation.

Pub. Date : 2006 Oct 4

PMID : 16990799






2 Functional Relationships(s)
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1 An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation. Guanine Nucleotides eukaryotic translation initiation factor 2B subunit delta Homo sapiens
2 We propose that the eIF2/eIF5 complex represents a cytoplasmic reservoir for eIF2 that antagonizes eIF2B-promoted guanine nucleotide exchange, enabling coordinated regulation of translation initiation. Guanine Nucleotides eukaryotic translation initiation factor 2B subunit delta Homo sapiens