Title : Decreased suppression of interleukin-6 after treatment with medroxyprogesterone acetate and danazol in endometrial stromal cells of women with adenomyosis.

Pub. Date : 2006 Nov

PMID : 16989825






4 Functional Relationships(s)
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1 Decreased suppression of interleukin-6 after treatment with medroxyprogesterone acetate and danazol in endometrial stromal cells of women with adenomyosis. Danazol interleukin 6 Homo sapiens
2 RESULT(S): A significant decrease of IL-6 concentration in the supernatant, measured by ELISA, was found with time of ESCs cultured with MPA and danazol in the control group, but not in adenomyosis. Danazol interleukin 6 Homo sapiens
3 The IL-6 mRNA in ESCs determined by real-time quantitative polymerase chain, as well as its concentration in the supernatant, was much higher in adenomyosis than that in the control group after treatment with MPA and danazol for 8 days. Danazol interleukin 6 Homo sapiens
4 CONCLUSION(S): Medroxyprogesterone acetate and danazol appeared to have a decreased effect on the suppression of IL-6 liberated by ESCs in adenomyosis. Danazol interleukin 6 Homo sapiens