Pub. Date : 2006 Dec
PMID : 16988013
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In A549 pulmonary cells, dexamethasone and the prototypical dissociated ligand RU24858 (Mol Endocrinol 11:1245-1255, 1997) repress interleukin (IL)-1beta-induced expression of cyclooxygenase (COX)-2 and IL-8. | Dexamethasone | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 2 | Analysis of IL-1beta-induced steady-state mRNA levels for IL-8 and COX-2 show that dexamethasone- and RU24858-dependent repression of these genes is attenuated by inhibitors of transcription and protein synthesis. | Dexamethasone | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |