Title : Cytokine expression and AIF-1-mediated activation of Rac2 in vascular smooth muscle cells: a role for Rac2 in VSMC activation.

Pub. Date : 2007 Feb

PMID : 16987989






1 Functional Relationships(s)
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1 Retroviral overexpression of Rac2 in primary VSMC leads to increased migration, activation of the NADPH oxidation cascade, and increased activation of the Rac2 effector protein Pak1 and its proximal effectors, ERK1/2, and p38 (P < 0.05 for all). NADP Rac family small GTPase 2 Homo sapiens