Title : Novel therapies for Crohn's disease: focus on immunomodulators and antibiotics.

Pub. Date : 2006 Oct

PMID : 16985094






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1 OBJECTIVE: To review the literature on novel immunomodulators such as tumor necrosis factor alpha (TNF-alpha)- and interleukin (IL)-related agents, 6-thioguanine (6-TG), tacrolimus, and leflunomide, and antibiotics such as ornidazole, rifaximin, and ciprofloxacin for the treatment of Crohn"s disease. Tacrolimus tumor necrosis factor Homo sapiens