Title : Intracellular inhibition of carboxylesterases by benzil: modulation of CPT-11 cytotoxicity.

Pub. Date : 2006 Sep

PMID : 16985062






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We have recently identified two classes of carboxylesterase inhibitors based on either a benzil (diphenylethane-1,2-dione) or a benzene sulfonamide scaffold and showed that these compounds inhibit carboxylesterases with Kis in the low nanomolar range. benzil U2AF homology motif kinase 1 Homo sapiens
2 We have recently identified two classes of carboxylesterase inhibitors based on either a benzil (diphenylethane-1,2-dione) or a benzene sulfonamide scaffold and showed that these compounds inhibit carboxylesterases with Kis in the low nanomolar range. benzil U2AF homology motif kinase 1 Homo sapiens