Title : Small-molecule screening identifies the selanazal drug ebselen as a potent inhibitor of DMT1-mediated iron uptake.

Pub. Date : 2006 Sep

PMID : 16984886






1 Functional Relationships(s)
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1 These observations indicate that Fe(II) transport by DMT1 can be modulated by cellular redox status and suggest that ebselen may act therapeutically to limit iron-catalyzed damage due to transport inhibition. ammonium ferrous sulfate solute carrier family 11 member 2 Homo sapiens