Pub. Date : 2007 Jan 25
PMID : 16983346
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | An increase of the HR rate enhanced by Vpr was attenuated by an ATM inhibitor, KU55933, suggesting that Vpr-induced DSBs activate ATM-dependent cellular signal that enhances the intracellular recombination potential. | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | Vpr | Human immunodeficiency virus 1 |
| 2 | An increase of the HR rate enhanced by Vpr was attenuated by an ATM inhibitor, KU55933, suggesting that Vpr-induced DSBs activate ATM-dependent cellular signal that enhances the intracellular recombination potential. | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | Vpr | Human immunodeficiency virus 1 |
| 3 | In context with a recent report that KU55933 attenuated the integration of HIV-1 into host genomes, we discuss the possible role of Vpr-induced DSBs in viral integration and also in HIV-1 associated malignancy. | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | Vpr | Human immunodeficiency virus 1 |