Title : Adenomatous polyposis coli determines sensitivity to histone deacetylase inhibitor-induced apoptosis in colon cancer cells.

Pub. Date : 2006 Sep 15

PMID : 16982769






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 HCA-7 cells (expressing wild-type beta-catenin and APC proteins) are more sensitive to apoptosis induced by HDAC inhibitors valproic acid (VPA) and suberoylanilide hydroxamic acid than SW620 or HT-29 cells (both expressing mutant APC). Valproic Acid catenin beta 1 Homo sapiens
2 HCA-7 cells (expressing wild-type beta-catenin and APC proteins) are more sensitive to apoptosis induced by HDAC inhibitors valproic acid (VPA) and suberoylanilide hydroxamic acid than SW620 or HT-29 cells (both expressing mutant APC). Valproic Acid catenin beta 1 Homo sapiens