Title : Termination of DNA synthesis by 9-beta-D-arabinofuranosyl-2-fluoroadenine. A mechanism for cytotoxicity.

Pub. Date : 1990 Sep 25

PMID : 1697861






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Human DNA polymerase alpha incorporated more F-ara-AMP into DNA than polymerase epsilon (proliferating cell nuclear antigen-independent DNA polymerase delta) and was more sensitive to inhibition by F-ara-ATP. fludarabine phosphate DNA polymerase alpha 1, catalytic subunit Homo sapiens