Title : Insights into the o-acetylation reaction of hydroxylated heterocyclic amines by human arylamine N-acetyltransferases: a computational study.

Pub. Date : 2006 Sep

PMID : 16978022






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Docking studies of hydroxylated heterocyclic amines in the models of NAT1 and NAT2 probed the differences exhibited by these two proteins with mutagenic agents. Amines N-acetyltransferase 2 Homo sapiens
2 The hydroxylated heterocyclic amines were only able to fit into the NAT2 active site, and an alternative binding site by the phosphate-binding loop was found using our models and will be discussed. Amines N-acetyltransferase 2 Homo sapiens