Title : Pyridostigmine potentiates L-dopa- but not arginine- and galanin-induced growth hormone secretion in children.

Pub. Date : 1990 Jul

PMID : 1697660






2 Functional Relationships(s)
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1 In 8 children, PD and L-dopa when administered alone induced an equivalent GH rise (area under the response curve, mean +/- SEM: 241.4 +/- 31.1 vs. 202.9 +/- 38.6 micrograms/l/h) while their coadministration had an additive effect (435.4 +/- 41.4 micrograms/l/h; p less than 0.02 vs. PD and L-dopa alone). Levodopa growth hormone 1 Homo sapiens
2 These data show that the enhancement of the cholinergic activity by PD increases the L-dopa-induced GH release but fails to modify both Arg- and GAL-induced GH release in short children. Levodopa growth hormone 1 Homo sapiens