Title : Activation of pregnane X receptor disrupts glucocorticoid and mineralocorticoid homeostasis.

Pub. Date : 2007 Jan

PMID : 16973756






1 Functional Relationships(s)
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1 Activation of PXR by genetic (transgene) or pharmacological (ligand, such as rifampicin) markedly increased plasma concentrations of corticosterone and aldosterone, the respective primary glucocorticoid and mineralocorticoid in rodents. Rifampin nuclear receptor subfamily 1, group I, member 2 Mus musculus