Pub. Date : 2006 Nov
PMID : 16968805
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Lovastatin significantly decreased Rho kinase and nuclear factor-kappaB activity, significantly increased Akt activity, and resulted in decreased monocyte IL-6 levels; these effects were reversed with mevalonate and geranylgeranyl pyrophosphate, indicating direct effects of statins on protein prenylation. | Lovastatin | AKT serine/threonine kinase 1 | Homo sapiens |