Title : 2,3-butanedione monoxime affects cystic fibrosis transmembrane conductance regulator channel function through phosphorylation-dependent and phosphorylation-independent mechanisms: the role of bilayer material properties.

Pub. Date : 2006 Dec

PMID : 16966478






1 Functional Relationships(s)
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1 In guinea pig ventricular myocytes, forskolin-activated whole-cell CFTR currents responded biphasically to external 20 mM BDM: a rapid approximately 2-fold current activation was followed by a slower (tau approximately 20 s) inhibition (to approximately 20% of control). Colforsin ATP-binding cassette sub-family C member 7 Cavia porcellus