Pub. Date : 2006
PMID : 16965246
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Diallyl trisulfide inhibits angiogenic features of human umbilical vein endothelial cells by causing Akt inactivation and down-regulation of VEGF and VEGF-R2. | diallyl trisulfide | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | We have shown recently that diallyl trisulfide (DATS), a cancer-chemopreventive constituent of garlic, inactivates Akt to trigger mitochondrial translocation of proapoptotic protein BAD in human prostate cancer cells. | diallyl trisulfide | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | We have shown recently that diallyl trisulfide (DATS), a cancer-chemopreventive constituent of garlic, inactivates Akt to trigger mitochondrial translocation of proapoptotic protein BAD in human prostate cancer cells. | diallyl trisulfide | AKT serine/threonine kinase 1 | Homo sapiens |
| 4 | DATS treatment inhibited the formation of capillary-like tube structure and migration by HUVECs in association with suppression of vascular endothelial growth factor (VEGF) secretion and VEGF receptor-2 protein level and inactivation of Akt kinase. | diallyl trisulfide | AKT serine/threonine kinase 1 | Homo sapiens |