Title : A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis.

Pub. Date : 2006

PMID : 16963491






1 Functional Relationships(s)
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1 Interestingly, when loop1 from TdT was inserted in Polmu (substituting its cognate loop1), the resulting chimaera displayed TdT activity, preferentially inserting dGTP residues, but had a strongly reduced template-dependent polymerization activity. deoxyguanosine triphosphate DNA polymerase mu Homo sapiens