Title : Phospholipase B activity and organophosphorus compound toxicity in cultured neural cells.

Pub. Date : 2007 Mar

PMID : 16963094






5 Functional Relationships(s)
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1 Organophosphorus compounds (OP) such as phenyl saligenin phosphate (PSP) and mipafox (MPX) which cause delayed neuropathy, inhibit neuropathy target esterase (NTE), while OPs such as paraoxon (PXN) react more readily with acetylcholinesterase. mipafox patatin-like phospholipase domain containing 6 Mus musculus
2 Organophosphorus compounds (OP) such as phenyl saligenin phosphate (PSP) and mipafox (MPX) which cause delayed neuropathy, inhibit neuropathy target esterase (NTE), while OPs such as paraoxon (PXN) react more readily with acetylcholinesterase. mipafox patatin-like phospholipase domain containing 6 Mus musculus
3 Organophosphorus compounds (OP) such as phenyl saligenin phosphate (PSP) and mipafox (MPX) which cause delayed neuropathy, inhibit neuropathy target esterase (NTE), while OPs such as paraoxon (PXN) react more readily with acetylcholinesterase. mipafox patatin-like phospholipase domain containing 6 Mus musculus
4 Organophosphorus compounds (OP) such as phenyl saligenin phosphate (PSP) and mipafox (MPX) which cause delayed neuropathy, inhibit neuropathy target esterase (NTE), while OPs such as paraoxon (PXN) react more readily with acetylcholinesterase. mipafox patatin-like phospholipase domain containing 6 Mus musculus
5 In cortical and cerebellar granule neurons and astrocytes, [(14)C]GroPCho labeling was inhibited by PSP and MPX: phenyl dipentylphosphinate (PDPP), a non-neuropathic NTE inhibitor, was more potent, while PXN, was substantially less so. mipafox patatin-like phospholipase domain containing 6 Mus musculus