Title : Cysteine 98 in CYP3A4 contributes to conformational integrity required for P450 interaction with CYP reductase.

Pub. Date : 2006 Oct 1

PMID : 16959210






1 Functional Relationships(s)
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1 In addition, the C98W mutant exhibited a 41% decrease in the maximum electron flow rate between P450 and reductase as measured by reduced nicotinamide adenine dinucleotide phosphate consumption at a saturating reductase concentration. NADP cytochrome P450 family 2 subfamily B member 6 Homo sapiens