Title : Identification of binding sites of non-I-helix water molecules in mammalian cytochromes p450.

Pub. Date : 2006 Dec

PMID : 16956955






1 Functional Relationships(s)
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1 Therefore, it is possible that some of the water binding sites identified here ultimately determine P450 catalytic efficiency either by working as an extension of the I-helix water network, or by acting in novel proton shuttles that modulate the nonproductive shunting of reactive oxygen species. Reactive Oxygen Species cytochrome P450 family 2 subfamily B member 6 Homo sapiens