Pub. Date : 2006 Aug
PMID : 16946558
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Furthermore, uptake of fexofenadine by Xenopus oocytes expressing rat oatp3 was significantly greater than that by water-injected oocytes, and the affinity of oatp3 for fexofenadine (Km) was about 60 microM, which is comparable with the value obtained by the Ussing chamber method using rat intestinal tissues. | fexofenadine | solute carrier organic anion transporter family, member 1A5 | Rattus norvegicus |
2 | Furthermore, uptake of fexofenadine by Xenopus oocytes expressing rat oatp3 was significantly greater than that by water-injected oocytes, and the affinity of oatp3 for fexofenadine (Km) was about 60 microM, which is comparable with the value obtained by the Ussing chamber method using rat intestinal tissues. | fexofenadine | solute carrier organic anion transporter family, member 1A5 | Rattus norvegicus |
3 | Furthermore, uptake of fexofenadine by Xenopus oocytes expressing rat oatp3 was significantly greater than that by water-injected oocytes, and the affinity of oatp3 for fexofenadine (Km) was about 60 microM, which is comparable with the value obtained by the Ussing chamber method using rat intestinal tissues. | fexofenadine | solute carrier organic anion transporter family, member 1A5 | Rattus norvegicus |
4 | These results indicate that oatp3 plays a role as an influx transporter in the intestinal absorption of fexofenadine in rats. | fexofenadine | solute carrier organic anion transporter family, member 1A5 | Rattus norvegicus |