Title : Characterization of humanized liver from chimeric mice using coumarin as a human CYP2A6 and mouse CYP2A5 probe.

Pub. Date : 2006 Aug

PMID : 16946554






2 Functional Relationships(s)
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Protein Name
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1 Characterization of humanized liver from chimeric mice using coumarin as a human CYP2A6 and mouse CYP2A5 probe. coumarin cytochrome P450 family 2 subfamily A member 6 Homo sapiens
2 Coumarin 7-hydroxylation (COH), which is catalyzed almost solely by human CYP2A6 and mouse CYP2A5, shows large differences in activity (humans>>mice) and inhibitor specificity between mice and humans. coumarin cytochrome P450 family 2 subfamily A member 6 Homo sapiens