Title : Contribution of CYP2C9, CYP2A6, and CYP2B6 to valproic acid metabolism in hepatic microsomes from individuals with the CYP2C9*1/*1 genotype.

Pub. Date : 2006 Dec

PMID : 16945988






1 Functional Relationships(s)
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1 cDNA-expressed CYP2C9*1, CYP2A6, and CYP2B6 were the most active catalysts of 4-ene-VPA, 4-OH-VPA, and 5-OH-VPA formation. 5-Hydroxyvalproic acid cytochrome P450 family 2 subfamily B member 6 Homo sapiens