Title : Expression profiling of ATP-binding cassette transporters in childhood T-cell acute lymphoblastic leukemia.

Pub. Date : 2006 Aug

PMID : 16928819






3 Functional Relationships(s)
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1 Treatment of CCRF-CEM and Jurkat cells with methotrexate, vinblastine, or doxorubicin led to an induction of ABCA3 expression, whereas a significant increase of ABCA2 expression was only observed in Jurkat cells. Methotrexate ATP binding cassette subfamily A member 2 Homo sapiens
2 Upon cotreatment of RNAi for ABCA2 with methotrexate and vinblastine, a partial decrease of ABCA2 expression as well as a simultaneous increase of ABCA3 expression was observed. Methotrexate ATP binding cassette subfamily A member 2 Homo sapiens
3 Upon cotreatment of RNAi for ABCA2 with methotrexate and vinblastine, a partial decrease of ABCA2 expression as well as a simultaneous increase of ABCA3 expression was observed. Methotrexate ATP binding cassette subfamily A member 2 Homo sapiens