Title : Differences in conformational stability between native and phosphorylated acetylcholinesterase as evidenced by a monoclonal antibody.

Pub. Date : 1990 Mar 13

PMID : 1692236






1 Functional Relationships(s)
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Protein Name
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1 Monoclonal antibody 25B1 appears to be directed against a conformational epitope located in close proximity to the catalytic center of the enzyme and was found to be most suitable for studying the stabilization of the active site of acetylcholinesterase against denaturation by heat or guanidine following phosphorylation by organophosphorus anticholinesterase compounds. Guanidine acetylcholinesterase (Cartwright blood group) Homo sapiens