Title : Suppression of hypoxia inducible factor-1alpha (HIF-1alpha) by YC-1 is dependent on murine double minute 2 (Mdm2).

Pub. Date : 2006 Oct 6

PMID : 16919599






1 Functional Relationships(s)
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1 Recently, 3-(5"-hydroxymethyl-2"-furyl)-1-benzyl indazole (YC-1) has been identified as an anti-HIF-1alpha drug in cancer therapy with unclear molecular mechanism. 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole hypoxia inducible factor 1, alpha subunit Mus musculus