CPRiL

3 Functional Relationships(s) Download
	Sentence	Compound Name	Protein Name	Organism
1	It is generally assumed that SLC26A4 acts as a chloride/anion exchanger, which in the thyroid gland transports iodide, and in the inner ear contributes to the conditioning of the endolymphatic fluid.	Iodides	solute carrier family 26 member 4	Homo sapiens
2	The validation of the method was done by functionally characterizing the chloride/iodide transport of SLC26A4, and a mutant, i.e. SLC26A4(S28R), which we previously described in a patient with sensorineural hearing loss, hypothyroidism and goiter.	Iodides	solute carrier family 26 member 4	Homo sapiens
3	Using the fluorometric method we describe here we can continuously monitor and quantify the iodide or chloride amounts transported by the cells, and we found that the transport capability of the SLC26A4(S28R) mutant protein is markedly reduced if compared to wild-type SLC26A4.	Iodides	solute carrier family 26 member 4	Homo sapiens