Title : Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1.

Pub. Date : 2006 Sep

PMID : 16906159






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In T cells, the SH2 domain of GRB2 binds phosphorylated tyrosines on the adaptor protein LAT and the GRB2 SH3 domains associate with the proline-rich regions of SOS1 and CBL. Proline growth factor receptor bound protein 2 Homo sapiens
2 In T cells, the SH2 domain of GRB2 binds phosphorylated tyrosines on the adaptor protein LAT and the GRB2 SH3 domains associate with the proline-rich regions of SOS1 and CBL. Proline growth factor receptor bound protein 2 Homo sapiens