Title : A Src homology 3-binding sequence on the C terminus of Sprouty2 is necessary for inhibition of the Ras/ERK pathway downstream of fibroblast growth factor receptor stimulation.

Pub. Date : 2006 Oct 6

PMID : 16893902






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Spry2 is considerably more inhibitory than Spry1 or Spry4, and this correlates with the binding to Grb2 via a C-terminal proline-rich sequence that is found exclusively on Spry2. Proline growth factor receptor bound protein 2 Homo sapiens