Title : Inhibition of the signaling pathways for macrophage proliferation by cyclic AMP. Lack of effect on early responses to colony stimulating factor-1.

Pub. Date : 1990 Feb 15

PMID : 1689293






1 Functional Relationships(s)
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1 In this report we show that several agents which raise intracellular cAMP (8-bromoadenosine 3":5"-cyclic monophosphate, 3-isobutyl-1-methylxanthine, cholera toxin, and prostaglandin E2) reversibly inhibit DNA synthesis in BMM induced by CSF-1, granulocyte macrophage-colony stimulating factor, interleukin-3, and PMA. Cyclic AMP interleukin 3 Mus musculus