Title : Focused libraries of 16-substituted estrone derivatives and modified e-ring steroids: inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

Pub. Date : 2006 Apr

PMID : 16892382






1 Functional Relationships(s)
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Protein Name
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1 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1), an oxidoreductase which has a preferential reductive activity using NADPH as cofactor, converts estrone to estradiol and is expressed in many steroidogenic tissues including breast and in malignant breast cells. NADP RNA, U1 small nuclear 1 Homo sapiens