Title : Calpain mediates the dioxin-induced activation and down-regulation of the aryl hydrocarbon receptor.

Pub. Date : 2006 Nov

PMID : 16891617






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The aryl hydrocarbon receptor (AhR) is a ligand-activated basic-helix-loop-helix transcription factor that binds polyaromatic hydrocarbons (PAH), such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), and mediates their toxicity. p-Aminohippuric Acid aryl-hydrocarbon receptor Mus musculus
2 The aryl hydrocarbon receptor (AhR) is a ligand-activated basic-helix-loop-helix transcription factor that binds polyaromatic hydrocarbons (PAH), such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), and mediates their toxicity. p-Aminohippuric Acid aryl-hydrocarbon receptor Mus musculus
3 Binding of PAH to AhR in the cytoplasm triggers a poorly defined transformation step of the receptor into a nuclear transcription factor. p-Aminohippuric Acid aryl-hydrocarbon receptor Mus musculus