Title : Platelet-derived growth factor-stimulated c-myc RNA accumulation in MG-63 human osteosarcoma cells is independent of both protein kinase A and protein kinase C.

Pub. Date : 1990 Jan

PMID : 1688464






2 Functional Relationships(s)
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Protein Name
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1 These data suggest that cAMP, phorbol esters, and PDGF act independently to stimulate c-myc RNA expression in MG-63 cells. Phorbol Esters MYC proto-oncogene, bHLH transcription factor Homo sapiens
2 However, nuclear runoff experiments and RNA half-life measurements demonstrated that PDGF, phorbol ester, and cAMP all act to increase the transcription of the MYC gene. Phorbol Esters MYC proto-oncogene, bHLH transcription factor Homo sapiens