Title : Carbamylcholine and phorbol esters desensitize muscarinic receptors by different mechanisms in rat pancreatic acini.

Pub. Date : 1990

PMID : 1688390






1 Functional Relationships(s)
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1 Pretreatment of rat pancreatic acini with phorbol 12-myristate, 13-acetate (PMA), a protein kinase C (PK-C) activator, caused the desensitization of carbamylcholine (CBC)-induced amylase release in a concentration- and time-dependent fashion. Carbachol protein kinase C, gamma Rattus norvegicus