Title : Wnt-5a/Ca2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase 1alpha signaling in human mammary epithelial cells.

Pub. Date : 2006 Aug

PMID : 16880514






2 Functional Relationships(s)
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1 The observation that inhibition of the Wnt-5a/Yes/Cdc42 signal prolonged the duration of ionomycin-induced NFAT1 activation revealed the general importance of this pathway. Ionomycin nuclear factor of activated T cells 2 Homo sapiens
2 Instead, we observed that Wnt-5a induced a complex formation of NFAT1/casein kinase 1alpha, even upon treatment with ionomycin, which was blocked upon inhibition of the Wnt-5a/Yes/Cdc42 signaling pathway. Ionomycin nuclear factor of activated T cells 2 Homo sapiens