Title : Dynamic changes in chromatin acetylation and the expression of histone acetyltransferases and histone deacetylases regulate the SM22alpha transcription in response to Smad3-mediated TGFbeta1 signaling.

Pub. Date : 2006 Sep 22

PMID : 16876108






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We also found that TSA, a HDAC inhibitor that stimulates histone acetylation of the SM22alpha locus, further enhances the transactivational activity of Smad2, Smad3 and Smad4, and relieves the inhibitory effect of Smad6, Smad7, and the dominant negative mutants of Smads. trichostatin A SMAD family member 3 Homo sapiens