Title : Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis.

Pub. Date : 2007 Jan

PMID : 16874462






3 Functional Relationships(s)
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1 Previously we showed that overexpression of POX is associated with generation of reactive oxygen species (ROS) and apoptosis in POX-inducible colorectal cancer cells, DLD-1.POX. Reactive Oxygen Species proline dehydrogenase 1 Homo sapiens
2 Previously we showed that overexpression of POX is associated with generation of reactive oxygen species (ROS) and apoptosis in POX-inducible colorectal cancer cells, DLD-1.POX. Reactive Oxygen Species proline dehydrogenase 1 Homo sapiens
3 We also showed expression of mitochondrial MnSOD partially blunts POX-induced ROS generation and apoptosis. Reactive Oxygen Species proline dehydrogenase 1 Homo sapiens