Title : TNF receptor superfamily-induced cell death: redox-dependent execution.

Pub. Date : 2006 Aug

PMID : 16873882






1 Functional Relationships(s)
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1 Recently, some important discoveries have underscored the critical role of ROS in TNFalpha signaling, notably in TNFalpha-mediated activation of nuclear factor-kappaB (NF-kappaB) and c-Jun N-terminal kinase (c-Jun NH2-terminal kinase, JNK), as well as in cell death (apoptotic and necrotic) pathways. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens