Title : N-hexacosanol ameliorates streptozotocin-induced diabetic rat nephropathy.

Pub. Date : 2006 Aug 21

PMID : 16859672






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1 The malonaldehyde and transforming growth factor beta-1 (TGF-beta1) concentrations as well as the protein kinase C (PKC) activities in the diabetic kidney were significantly higher than those of the control, which were decreased by treatment with N-hexacosanol. 1-hexacosanol transforming growth factor, beta 1 Rattus norvegicus
2 The malonaldehyde and transforming growth factor beta-1 (TGF-beta1) concentrations as well as the protein kinase C (PKC) activities in the diabetic kidney were significantly higher than those of the control, which were decreased by treatment with N-hexacosanol. 1-hexacosanol transforming growth factor, beta 1 Rattus norvegicus
3 Our data suggest that N-hexacosanol could prevent increases in the malonaldehyde and TGF-beta1 concentrations and PKC activities in the kidney, and ameliorate diabetic-induced nephropathy. 1-hexacosanol transforming growth factor, beta 1 Rattus norvegicus